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J Am Med Inform Assoc 2005;12:35-46 doi:10.1197/jamia.M1401
  • The Practice of Informatics
  • Application of Information Technology

Processes and Problems in the Formative Evaluation of an Interface to the Foundational Model of Anatomy Knowledge Base

  1. Linda G Shapiro,
  2. Emily Chung,
  3. Landon T Detwiler,
  4. José L V Mejino Jr,
  5. Augusto V Agoncillo,
  6. James F Brinkley,
  7. Cornelius Rosse
  1. Affiliation of the authors: Structural Informatics Group (LGS, EC, LTD, JLVM, AVA, JFB, CR), Department of Biological Structure (LTD, JLVM, AVA, JFB, CR), Department of Medical Education and Biomedical Informatics (LGS, JFB), Department of Computer Science and Engineering (LGS, EC, JFB) and the Department of Electrical Engineering (LGS), University of Washington, Seattle, WA
  1. Correspondence and reprints: Linda G. Shapiro, PhD, Box 352350, Computer Science and Engineering, 634 Paul Allen Center, University of Washington, Seattle, WA 98195; e-mail: <shapiro{at}cs.washington.edu>
  • Received 27 May 2003
  • Accepted 7 September 2004

Abstract

The Digital Anatomist Foundational Model of Anatomy (FMA) is a large semantic network of more than 100,000 terms that refer to the anatomical entities, which together with 1.6 million structural relationships symbolically represent the physical organization of the human body. Evaluation of such a large knowledge base by domain experts is challenging because of the sheer size of the resource and the need to evaluate not just classes but also relationships. To meet this challenge, the authors have developed a relation-centric query interface, called Emily, that is able to query the entire range of classes and relationships in the FMA, yet is simple to use by a domain expert. Formative evaluation of this interface considered the ability of Emily to formulate queries based on standard anatomy examination questions, as well as the processing speed of the query engine. Results show that Emily is able to express 90% of the examination questions submitted to it and that processing time is generally 1 second or less, but can be much longer for complex queries. These results suggest that Emily will be a very useful tool, not only for evaluating the FMA, but also for querying and evaluating other large semantic networks.

Footnotes

  • Supported by National Library of Medicine grants LM007714 and LM06822 and Human Brain Project grant DC02310.

  • The name Emily is in honor of the second author, Emily Chung, who developed the initial prototype of this program as a summer undergraduate project.

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