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J Am Med Inform Assoc 2005;12:207-216 doi:10.1197/jamia.M1641
  • Original Investigation
  • Research Paper

Text Categorization Models for High-Quality Article Retrieval in Internal Medicine

  1. Yindalon Aphinyanaphongs,
  2. Ioannis Tsamardinos,
  3. Alexander Statnikov,
  4. Douglas Hardin,
  5. Constantin F Aliferis
  1. Affiliations of the authors: Departments of Biomedical Informatics (YA, IT, AS, CFA) and Mathematics (DH), Vanderbilt University, Nashville TN
  1. Correspondence and reprints: Yindalon Aphinyanaphongs, MS, Department of Biomedical Informatics, 4th Floor, Eskind Biomedical Library, 2209 Garland Avenue, Vanderbilt University, Nashville, TN 37232.; e-mail: <ping.pong{at}vanderbilt.edu>
  • Received 17 June 2004
  • Accepted 17 November 2004

Abstract

Objective Finding the best scientific evidence that applies to a patient problem is becoming exceedingly difficult due to the exponential growth of medical publications. The objective of this study was to apply machine learning techniques to automatically identify high-quality, content-specific articles for one time period in internal medicine and compare their performance with previous Boolean-based PubMed clinical query filters of Haynes et al.

Design The selection criteria of the ACP Journal Club for articles in internal medicine were the basis for identifying high-quality articles in the areas of etiology, prognosis, diagnosis, and treatment. Naïve Bayes, a specialized AdaBoost algorithm, and linear and polynomial support vector machines were applied to identify these articles.

Measurements The machine learning models were compared in each category with each other and with the clinical query filters using area under the receiver operating characteristic curves, 11-point average recall precision, and a sensitivity/specificity match method.

Results In most categories, the data-induced models have better or comparable sensitivity, specificity, and precision than the clinical query filters. The polynomial support vector machine models perform the best among all learning methods in ranking the articles as evaluated by area under the receiver operating curve and 11-point average recall precision.

Conclusion This research shows that, using machine learning methods, it is possible to automatically build models for retrieving high-quality, content-specific articles using inclusion or citation by the ACP Journal Club as a gold standard in a given time period in internal medicine that perform better than the 1994 PubMed clinical query filters.

Footnotes

  • Supported by the Vanderbilt MSTP program and NLM grant LM007948-02.

  • A preliminary report on a portion of this work appeared in AMIA Annu Sympos Proc 2003[30].

  • The authors thank Dr. Randolph Miller, the anonymous reviewers, and the senior editor for their valuable comments and suggestions.

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