Table 4
Most Frequent Override Reasons Provided by Clinician
| Contraindication | Override Reasons (%) |
| Duplicate class | Transitioning from one medication to other (42) |
| Patient is on long-term therapy with combination (21) | |
| Short-term or as-needed dosing (7) | |
| Drug-drug | Will monitor as recommended (49) |
| Patient has already tolerated combination (21) | |
| Will adjust dose as recommended (14) | |
| Drug-lab | Will monitor/manage as recommended (67) |
| More recent lab result available that warrants use (18) | |
| Drug-disease | Patient has tolerated this drug in the past (56) |
| New evidence supports therapy of this type (22) | |
| Drug-pregnancy | Patient is not pregnant (90) |
| Patient is not of child-bearing potential (5) |
