Performance of IR-1, IR-1’, and TC-1 in the Derivation Set, and Validation Set (TC-1)
| X-ray Reports | Method | TP FP | FN TN | Sensitivity, % (95% CI) | Specificity, % (95% CI) | PPV, % (95% CI) | Accuracy, % (95% CI) |
| Derivation set (n = 493) | IR-1 | 110 | 103 | 51.6 | 97.5 | 94.0 | 77.7 |
| 7 | 273 | (45.0–58.3) | (94.9–98.8) | (88.2–97.1) | (73.7–81.1) | ||
| IR-1’ | 145 | 68 | 68.1 | 91.8 | 86.3 | 81.5 | |
| 23 | 257 | (61.6–74.0) | (88.0–94.5) | (80.3–90.7) | (77.9–84.7) | ||
| IR-2 | 186 | 27 | 87.3 | 91.1 | 88.2 | 89.5 | |
| 25 | 255 | (82.2–91.1) | (87.2–93.9) | (83.1–91.8) | (86.4–91.9) | ||
| TC-1 | 200 | 13 | 93.9 | 93.6 | 91.7 | 93.7 | |
| 18 | 262 | (89.8–96.4) | (90.1–95.9) | (87.3–94.7) | (91.2–95.5) | ||
| Validation set (n = 258) | TC-1 | 84 | 4 | 95.5 | 92.9 | 87.5 | 93.8 |
| 12 | 158 | (88.9–98.2) | (88.1–95.9) | (79.4–92.7) | (90.2–96.2) |
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TP/FN/FP/TN = True/False Pos/Negative; Sensitivity = Recall, PPV = positive predictive value-precision. 95% confidence intervals are calculated using the Wilson procedure.









