Table 1
Proportion of Rapidly Discontinued Medication Orders Found to be Inappropriate: Analyzed by 15-Minute, 30-Minute, and 45-Minute Time Segments
| 15-minute slices | |||||||||
| Time to discontinuation | 1–15 m | 16–30 m | 31–45 m | 46–60 m | 61–75 m | 76–90 m | 91–105 m | 106–20 m | Total |
| Inappropriate | 10 (62.5%) | 16 (69.6%) | 9 (64.3%) | 8 (44.4%) | 7 (50.0%) | 2 (15.4%) | 4 (66.7%) | 7 (70.0%) | 63 (55.3%) |
| “Not” Inappropriate or undetermined | 6 (37.5%) | 7 (30.4%) | 5 (35.7%) | 10 (55.6%) | 7 (50.0%) | 11 (84.6%) | 2 (33.3%) | 3 (30.0%) | 51 (44.7%) |
| PPV (95% CI) | 63 (38–81) | 70 (49–84) | 62 (38–84) | 44 (24–66) | 50 (27–73) | 15 (5–43) | 67 (29–90) | 70 (39–89) | 55 (46–64) |
| 30-minute slices | |||||||||
| Time to discontinuation | 1–30 m | 31–60 m | 61–90 m | 91–120 m | Total | ||||
| Inappropriate orders | 26 (67%) | 17 (53%) | 8 (35%) | 12 (60%) | 63 (55%) | ||||
| “Not” inappropriate or undetermined orders | 13 (33%) | 15 (47%) | 15 (65%) | 8 (40%) | 51 (45%) | ||||
| PPV (95% CI) | 67 (51–79) | 53 (36–69) | 35 (19–55) | 60 (38–78) | 55 (46–64) | ||||
| 45-minute slices | |||||||||
| Time to discontinuation | 1–45 m | 46–90 m | 91–120 m | Total | |||||
| Inappropriate orders | 35 (66%) | 17 (38%) | 11 (69%) | 63 (55%) | |||||
| “Not” inappropriate or undetermined orders | 18 (34%) | 28 (62%) | 5 (31%) | 51 (45%) | |||||
| PPV (95% CI) | 66 (53–77) | 38 (25–52) | 69 (44–86) | 55 (46–64) | |||||
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Trend Analyses: When we considered time intervals up to 120 minutes, we detected a marginally significant trend (p = 0.06) with the Cochran-Armitage trend test. That same test also shows that the percentage of inappropriate orders decreases across time categories up to 90 minutes (p = 0.02).”
