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J Am Med Inform Assoc 16:47-53 doi:10.1197/jamia.M2559
  • Original Investigation

Effects of a Pharmacist-to-Dose Computerized Request on Promptness of Antimicrobial Therapy

Table 4

Secondary Data1 (%)

Study (N = 71 Orders) Control (N = 57 Orders) p Value
Medication errors of incorrect dose 5 (7) 18 (32) <0.001
Height and weight electronic entry (%) 68 (96) 36 (63) <0.001
Mean ± standard deviation, weight-based vancomycin dosing (mg/kg) 14.9 ± 1.5 13.9 ± 3.1 <0.001*
Dose adjustment for renal insufficiency† 22 (69) 10 (56) 0.45
  • 1 Analysis of medication orders for vancomycin and aminoglycosides.

  • * Variance F test used to detect a difference between standard deviations.

  • Renal insufficiency defined as creatinine clearance29 less than 40 milliliters/minute/1.73 m2 (n = 32 for study, n = 18 for control) and adjustment made for total daily dose of aminoglycoside or vancomycin.

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