rss
J Am Med Inform Assoc 16:371-379 doi:10.1197/jamia.M2846
  • Original Investigation

Prediction of Chronic Obstructive Pulmonary Disease (COPD) in Asthma Patients Using Electronic Medical Records

Table 3

Strength and Predictive Ability of Individual Network Variables

Variable Effect, OR Referent Group Single Variable AUROC (SE) p Value
Acute bronchitis and bronchiolitis 2.52 (1.86, 3.36) 0 0.52 (0.04) 0.013
Acute upper respiratory infections 1.74 (1.29, 2.30) 0 0.50 (0) 1
Age 0.81 (0.04) 1.22E-15
 45–64 6.19 (4.87, 7.97) 18–44
 65–74 10.78 (8.30, 14.13) 18–44
 75+ 9.95 (7.32, 13.57) 18–44
Diabetes mellitus 2.94 (2.09, 4.06) 0 0.51 (0.02) 0.18
Heart Failure 4.69 (3.82, 5.75) 0 0.50 (0) 1
Pneumonia, organism unspecified 5.79 (4.93, 6.80) 0 0.59 (0.06) 1.86E-06
Race 0.50 (0) 1
 Asian 0.66 (0.29, 1.27) White
 Black 0.91 (0.72, 1.12) White
 Hispanic 0.61 (0.47, 0.77) White
Respiratory distress or insufficiency 5.97 (4.87, 7.30) 0 0.56 (0.05) 2.59E-08
Sex 1.74 (1.50, 2.02) female 0.53 (0.05) 0.17
Shortness of breath 6.34 (5.28, 7.59) 0 0.57 (0.05) 3.33E-05
Smoking history 12.67 (8.68, 19.43) negative 0.64 (0.01) 4.34E-05
Viral and chlamydial infections 1.05 (0.67, 1.58) 0 0.50 (0) 1
  • The second column reports odds ratios and 95% confidence intervals in parentheses.

  • The referent group refers to that used to compute the odds ratio.

  • The fourth column reports the AUROC of the network using the single variable data and corresponding standard errors (SE).

  • Fifth column p values correspond to comparison of single variable AUROC to a random classifier.

  • The network AUROC using all variables is 0.83 (p = 8.88E-15 compared to random).

  • AUROC = Area Under the Receiver Operating Characteristic curve.

This Article

Access policy for JAMIA

All content published in JAMIA is deposited with PubMed Central by the publisher with a 12 month embargo. Authors/funders may pay an Unlocked fee of $2,000 to make the article free on the JAMIA website and PMC immediately on publication.

All content older than 12 months is freely available on this website.

AMIA members can log in with their JAMIA user name (email address) and password or via the AMIA website.