Category of Alerts and Types of Alerts Showing a Beneficial Effect on Prescribing and/or Clinical Outcome
| Category of Drug Alerts | Number of Alert Types | Number of Studies with Beneficial Effect on Prescribing | Number of Studies with No Effect on Prescribing | Number of Studies with Positive Effect on Clinical Outcomes |
| Basic drug alerts | ||||
| 1. Drug allergy warnings | 1 | 124 | — | — |
| 2. Drug–drug interactions | 1 | — | 124 | — |
| 3. Duplication alerts | 0 | — | — | — |
| 4. Basic medication order guidance | 2 | 224 28 | — | — |
| Advanced drug alerts | ||||
| 1. Drug-laboratory alerts | 4 | 426 27 31 36 | — | 131 |
| 2. Drug-condition alerts | ||||
| 2a Drug–disease contraindication | 0 | — | — | — |
| 2b appropriate prescribing | 4 | 217 28 | 218 19 | — |
| 2c drug-age alerts | 4 | 330 34 35 | 133 | 130 |
| 3. Drug-formulary alerts | 4 | 421 23 28 32 | — | 221 32 |
| 4. Dosing guidelines based on: | ||||
| 4a Renal Function | 2 | 229 31 | — | 129 |
| 4b age | 0 | — | — | — |
| 4c pregnancy/childbearing potential | 0 | — | — | — |
| 4d Pediatric patients/weight based dosing | 1 | 120 | — | — |
| 4e indications | 0 | — | — | — |
| Combination of basic and advanced features | 4 | 422 24 25 28 | — | — |
| Total | 27 | 23 | 4 | 5 |
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Alert types showing beneficial effect on prescribing (second column), no effect on prescribing (third column) and positive effect on clinical outcomes (fourth column) compared to total number of alerts in a certain alert category (first column).









