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J Am Med Inform Assoc 16:889-898 doi:10.1197/jamia.M3085
  • Original Investigation

Translating Clinical Informatics Interventions into Routine Clinical Care: How Can the RE-AIM Framework Help?

Table 2

Illustration of Research Questions Assessing RE-AIM Dimensions in Two Case Studies

RE-AIM Dimension Choice PDA DSS
Reach (individual level)
  • What proportion of eligible patients was offered the Choice intervention at outpatient consultations, at admission, during hospital stay, or in preparation for discharge?

  • Which patients did not receive the intervention and why?

  • Were the patients who used or did not use the intervention representative of those eligible to use it?

  • What proportion of nurses and physicians actively use Choice assessment summaries to support patient-centered care and patient provider-communication?

  • Does Choice use vary by practice settings, and if so, why?

  • What proportion of nurses eligible to use the DSS actually used it?

  • In what proportion of eligible patient encounters was the DSS used?

  • Were the nurses who used the DSS representative of those eligible to use it?

  • Were the patient encounters in which the DSS was used representative of the eligible patient encounters?

Efficacy/effectiveness (individual level)
  • What is the effect of Choice on system outcomes (e.g., work processes; organizational change; interdisciplinary collaboration)?

  • What is the effect of Choice on provider outcomes (e.g., quality of care, congruence between symptoms reported and addressed, patient-provider communication, satisfaction)?

  • What is the effect of Choice on patient outcomes (e.g., symptom distress, quality of life, self-efficacy, satisfaction, participation in care)?

  • In what proportion of eligible encounters did screening for depression, obesity, or smoking occur?

  • Were there differences in the number of guideline-related diagnoses in DSS versus no DSS group?

  • Were there differences in the number of guideline-related interventions in DSS versus no DSS group?

Adoption (setting and/or organizational level)
  • What are the characteristics of the settings who decided to adopt Choice?

  • How well did the goals and values of Choice fit with the values and expectations of patients, nurses, and physicians?

  • How well did the goals of Choice fit with the values and expectations of the practice settings?

  • What proportion of patient encounters in DSS versus no DSS groups involved those who were Hispanic, African-American, or lacked private medical insurance?

  • Did DSS use help the Columbia University School of Nursing achieve its educational and practice missions?

  • Did DSS use help specific clinical practice sites achieve their practice missions?

Implementation (setting and/or organizational level)
  • How many nurses and physicians used Choice?

  • Did Choice use vary by unit?

  • Was Choice used as originally intended?

  • Did users perceive Choice as easy to use? (predisposing)

  • Did users perceive Choice as useful? (predisposing)

  • Was there sufficient leadership support and user buy-in? (predisposing)

  • What measures were needed to improve readiness for Choice adoption, commitment, and buy-in of practice settings? (enabling)

  • How were end-users involved in the Choice implementation process? (enabling)

  • What workflow adjustments needed to be made to streamline Choice into routines of daily clinical practice? (enabling)

  • What adjustments needed to be made to the Choice application itself? (enabling)

  • What were the confidentiality and data security issues when integrating Choice into routine practice and how were they addressed? (enabling)

  • What support, resources and outside collaborations were needed to implement Choice? (enabling)

  • Were the necessary resources and support available? (enabling)

  • What were the educational needs of Choice users? (enabling)

  • What were the potential barriers to successful Choice implementation and how were they addressed? (enabling)

  • How many nurses used the DSS?

  • Did DSS use vary according to time in Master's educational program?

  • Did DSS use vary by nursing specialty?

  • Did DSS use vary by guideline (depression versus obesity versus smoking cessation)?

  • Were DSS functions (screening, assessment, diagnosis, guideline-based plan of care template) used as intended?

  • What level of general PDA knowledge and DSS-specific knowledge was needed to use the DSS? (predisposing)

  • Did users perceive the DSS as easy to use? (predisposing)

  • Did users perceive the DSS as useful? (predisposing)

  • What user training and support services were needed by DSS users? (enabling)

  • What technical infrastructure was required to implement the DSS? (enabling)

Maintenance (individual and setting levels)
  • How did Choice evolve over time?

  • Did Choice produce lasting effects at individual level?

  • Did the units sustain Choice use over time?

  • What efforts were needed to maintain participation rate and effectiveness (e.g., repeated educational sessions concordant with staff turnover)? (reinforcing)

  • How did the DSS evolve over time?

  • Which reinforcing factors were useful (e.g., individual reports, aggregate reports by specialty, booster training sessions)?

  • DSS = decision support system; PDA = personal digital assistant; RE-AIM = Reach, Effectiveness, Adoption, Implementation, and Maintenance.

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