Randomized clinical trial of a customized electronic alert requiring an affirmative response compared to a control group receiving a commercial passive CPOE alert: NSAID–warfarin co-prescribing as a test case

Table 1

Frequency of alerts for warfarin and non-steroidal anti-inflammatory drugs (NSAIDs) that were followed by desired response by study group

	Study outcome		Statistical Results
Study group	Total alerts fired^* (alerts triggered by concurrent ordering of warfarin and NSAID)	Desired ordering responses (proportion of the alerts that were followed by an appropriate action (ie, the alert-triggering drug was not reordered within 10 min after the alert fired)	Unadjusted OR (95% CI)	Adjusted OR^† (95% CI)
Intervention group	464	114 (25%)	1.16 (0.88 to 1.54)	1.22 (0.69 to 2.16)
Control group	560	154 (28%)	1.16 (0.88 to 1.54)	1.22 (0.69 to 2.16)

↵* Counting as a single event alerts that were fired within ≤5 minutes of each other.
↵† Adjusted for study group, hospital, provider type, and clustering by provider type.

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