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J Am Med Inform Assoc 17:472-476 doi:10.1136/jamia.2010.003335
  • Case report

An unintended consequence of electronic prescriptions: prevalence and impact of internal discrepancies

Table 3

Potential for an ADE by class of conflicting information

Discrepancy class No PADE, N (%) Mild/moderate PADE, N (%) Severe PADE, N (%)
Complex regimen 6 (1.28) 100 (21.28) 31 (6.60)
Dosage range expanded inappropriately 4 (0.85) 66 (14.04) 6 (1.28)
Frequency mismatch 14 (2.98) 44 (9.36) 8 (1.70)
PRN mismatch 15 (3.19) 32 (6.81) 11 (2.34)
Dose mismatch 1 (0.21) 42 (8.94) 15 (3.19)
Imprecise conversion of daytime and around-the-clock frequencies 18 (3.83) 4 (0.85) 0
Frequency range extended inappropriately 8 (1.70) 9 (1.91) 2 (0.43)
Route mismatch 3 (0.64) 10 (2.13) 4 (0.85)
Dosage form mismatch 7 (1.49) 3 (0.64) 0
Duration mismatch 0 3 (0.64) 1 (0.21)
Quantity mismatch 0 2 (0.43) 0
Drug name mismatch 0 0 1 (0.21)
  • Percentages represent a fraction of total prescriptions examined.

  • ADE, adverse drug event; PADE, potential adverse drug event.

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