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JAMIA 1999;6:466-477 doi:10.1136/jamia.1999.0060466
  • The Practice of Informatics
  • Application of Information Technology

Pilot Study of a Point-of-use Decision Support Tool for Cancer Clinical Trials Eligibility

  1. Philip P Breitfeld,
  2. Marina Weisburd,
  3. J Marc Overhage,
  4. George Sledge Jr,
  5. William M Tierney
  1. Affiliation of the authors: Indiana University School of Medicine, Indianapolis, Indiana
  1. Corresdpondence and reprints: Philip P. Breitfeld, MD, National Library of Medicine Fellow in Medical Informatics, Regenstrief Institute, RG6, Indiana University School of Medicine, 1001 West Tenth Street, Indianapolis, IN 46202-2859. e-mail: 〈pbreitfe{at}iupui.edu〉
  • Received 21 January 1999
  • Accepted 17 May 1999

Abstract

Many adults with cancer are not enrolled in clinical trials because caregivers do not have the time to match the patient's clinical findings with varying eligibility criteria associated with multiple trials for which the patient might be eligible. The authors developed a point-of-use portable decision support tool (DS-TRIEL) to automate this matching process. The support tool consists of a hand-held computer with a programmable relational database. A two-level hierarchic decision framework was used for the identification of eligible subjects for two open breast cancer clinical trials. The hand-held computer also provides protocol consent forms and schemas to further help the busy oncologist. This decision support tool and the decision framework on which it is based could be used for multiple trials and different cancer sites.

Footnotes

  • This work was supported by medical informatics training grant 1T15-LM07117 from the National Library of Medicine and was conducted in affiliation with the Walther Cancer Institute.

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