Table 3
Performance Measures for Search Filters with High-accuracy Measures
| Search Filters* | Sensitivity (95% CI) | Specificity (95% CI) | Positive Predictive Value (95% CI) | Positive Likelihood Ratio (95% CI) |
| Filters with both sensitivity and specificity above 90%: | ||||
| 1—Validat$ OR Predict$.ti. OR Decision Support Techniques/ OR Rule$ OR Predictive Value of Tests/ | ||||
| 2—Predict$ AND (Clinical$ OR Identif$) | ||||
| 3—OR 1–2* | ||||
| Derivation set | 92.1% (83.3–97.0) | 94.2% (93.7–94.6) | 8.5% (6.5–10.9) | 15.8 (14.3–17.6) |
| Validation set | 91.1% (81.3–96.6) | 94.2% (93.8–94.6) | 7.5% (5.7–9.8) | 15.7 (14.1–17.6) |
| Predict$ OR Validat$ OR Rule$ OR | ||||
| Predictive Value of Tests/ | ||||
| Derivation set | 92.1% (83.3–97.0) | 92.8% (92.3–93.3) | 6.9% (5.3–8.9) | 12.8 (11.6–14.1) |
| Validation set | 91.1% (81.3–96.6) | 93.0% (92.5–93.5) | 6.3% (4.8–8.3) | 13.0 (11.7–14.5) |
| 1—Validat$ OR Predict$.ti. OR Decision Support Techniques/ OR Rule$ OR Predictive Value of Tests/ | ||||
| 2—Predict$ AND (Variable$ OR Factor$ OR Model$ OR Develop$ OR Sensitivit$ OR Clinical$ OR Independent$ OR Prospective OR Identif$) | ||||
| 3—Clinical$ AND (Independent$ OR Model$ OR Sensitivit$) | ||||
| Derivation set | 92.1% (83.3–97.0) | 90.8% (90.2–91.3) | 5.5% (4.2–7.1) | 10.0 (9.1–11.0) |
| Validation set | 92.9% (83.7–97.7) | 91.0% (90.5–91.6) | 5.1% (3.9–6.7) | 10.3 (9.4–11.4) |
| 4—OR 1–3* | ||||
| Predict$ OR Validat$ | ||||
| Derivation set | 90.5% (81.2–96.0) | 93.4% (93.0–93.9) | 7.4% (5.7–9.6)` | 13.8 (12.4–15.4) |
| Validation set | 85.7% (74.7–93.1) | 93.6% (93.1–94.0) | 6.4% (4.8–8.5) | 13.3 (11.7–15.1) |
| Top filters for positive predictive value and likelihood ratios: | ||||
| Decision Support Techniques/ AND Predictive Value of Tests/ | ||||
| Derivation set | 4.8% (1.2–12.4) | 100% (99.97–100.00) | 100% (31.0–100.0) | Undefined |
| Validation set | 1.8% (0.1–8.5) | 99.96% (99.90–99.99) | 20.0% (1.1–70.1) | 48 (5–425) |
| Decision Support Techniques/ AND Predict$.ti. | ||||
| Derivation set | 3.2% (0.5–10.1) | 100% (99.97–100.00) | 100% (19.8–100.00) | Undefined |
| Validation set | 1.8% (0.1–8.5) | 99.95% (99.89–99.98) | 16.7% (0.9–63.5) | 39 (5–326) |
| Predict$.ti. AND Rule$ | ||||
| Derivation set | 9.5% (4.0–18.8) | 99.99% (99.94–100.00) | 85.7% (42.0–99.2) | 1,030 (126–8,431) |
| Validation set | 16.1% (8.1–27.4) | 99.97% (99.91–99.99) | 75.0% (42.8–93.3) | 580 (161–2,085) |
-
↵* Numbers represent separately entered search statements. A slash (/) indicates a term searched as a subject heading.
