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J Am Med Inform Assoc 8:401-430 doi:10.1136/jamia.2001.0080401
  • Focus on Biomedical Imaging/Neuroscience

A Four-Dimensional Probabilistic Atlas of the Human Brain

Table 1

Distribution of the Apolipoprotein E ε4 Allele as a Function of Race in the U.S. Population, for Normal Subjects (Controls) and Patients with Alzheimer's Disease47

ε4 Homozygotes (%) ε4 Heterozygotes (%) ε4 Allele Frequency (%)
Caucasian:
 Controls 1.8 23.9 13.7
 Alzheimer's 14.8 43.7 36.7
African American:
 Controls 2.1 33.94 19
 Alzheimer's 12.3 40 32.2
Hispanic:
 Controls 1.9 18.4 11
 Alzheimer's 2.7 33 19.2
Japanese:
 Controls 0.8 16.3 8.9
 Alzheimer's 8.9 37.8 27.8

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