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<title>Journal of the American Medical Informatics Association</title>
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<title><![CDATA[The NIH National Center for Integrative Biomedical Informatics (NCIBI)]]></title>
<link>http://jamia.bmj.com/cgi/content/short/19/2/166?rss=1</link>
<description><![CDATA[
<p>The National Center for Integrative and Biomedical Informatics (NCIBI) is one of the eight NCBCs. NCIBI supports information access and data analysis for biomedical researchers, enabling them to build computational and knowledge models of biological systems to address the Driving Biological Problems (DBPs). The NCIBI DBPs have included prostate cancer progression, organ-specific complications of type 1 and 2 diabetes, bipolar disorder, and metabolic analysis of obesity syndrome. Collaborating with these and other partners, NCIBI has developed a series of software tools for exploratory analysis, concept visualization, and literature searches, as well as core database and web services resources. Many of our training and outreach initiatives have been in collaboration with the Research Centers at Minority Institutions (RCMI), integrating NCIBI and RCMI faculty and students, culminating each year in an annual workshop. Our future directions include focusing on the TranSMART data sharing and analysis initiative.</p>
]]></description>
<dc:creator><![CDATA[Athey, B. D., Cavalcoli, J. D., Jagadish, H. V., Omenn, G. S., Mirel, B., Kretzler, M., Burant, C., Isokpehi, R. D., DeLisi, C., the NCIBI faculty, trainees, and staff]]></dc:creator>
<dc:date>2012-02-07T16:14:26-08:00</dc:date>
<dc:identifier>info:doi/10.1136/amiajnl-2011-000552</dc:identifier>
<dc:identifier>hwp:master-id:amiajnl;amiajnl-2011-000552</dc:identifier>
<dc:publisher>American Medical Informatics Association</dc:publisher>
<dc:title><![CDATA[The NIH National Center for Integrative Biomedical Informatics (NCIBI)]]></dc:title>
<prism:publicationDate>2012-03-01</prism:publicationDate>
<prism:section>Brief communication</prism:section>
<prism:volume>19</prism:volume>
<prism:number>2</prism:number>
<prism:startingPage>166</prism:startingPage>
<prism:endingPage>170</prism:endingPage>
</item>
<item rdf:about="http://jamia.bmj.com/cgi/content/short/19/2/171?rss=1">
<title><![CDATA[Using systems and structure biology tools to dissect cellular phenotypes]]></title>
<link>http://jamia.bmj.com/cgi/content/short/19/2/171?rss=1</link>
<description><![CDATA[
<p>The Center for the Multiscale Analysis of Genetic Networks (MAGNet, <A HREF="http://magnet.c2b2.columbia.edu">http://magnet.c2b2.columbia.edu</A>) was established in 2005, with the mission of providing the biomedical research community with Structural and Systems Biology algorithms and software tools for the dissection of molecular interactions and for the interaction-based elucidation of cellular phenotypes. Over the last 7&nbsp;years, MAGNet investigators have developed many novel analysis methodologies, which have led to important biological discoveries, including understanding the role of the DNA shape in protein&ndash;DNA binding specificity and the discovery of genes causally related to the presentation of malignant phenotypes, including lymphoma, glioma, and melanoma. Software tools implementing these methodologies have been broadly adopted by the research community and are made freely available through geWorkbench, the Center's integrated analysis platform. Additionally, MAGNet has been instrumental in organizing and developing key conferences and meetings focused on the emerging field of systems biology and regulatory genomics, with special focus on cancer-related research.</p>
]]></description>
<dc:creator><![CDATA[Floratos, A., Honig, B., Pe'er, D., Califano, A.]]></dc:creator>
<dc:date>2012-02-07T16:14:26-08:00</dc:date>
<dc:identifier>info:doi/10.1136/amiajnl-2011-000490</dc:identifier>
<dc:identifier>hwp:master-id:amiajnl;amiajnl-2011-000490</dc:identifier>
<dc:publisher>American Medical Informatics Association</dc:publisher>
<dc:title><![CDATA[Using systems and structure biology tools to dissect cellular phenotypes]]></dc:title>
<prism:publicationDate>2012-03-01</prism:publicationDate>
<prism:section>Brief communication</prism:section>
<prism:volume>19</prism:volume>
<prism:number>2</prism:number>
<prism:startingPage>171</prism:startingPage>
<prism:endingPage>175</prism:endingPage>
</item>
<item rdf:about="http://jamia.bmj.com/cgi/content/short/19/2/176?rss=1">
<title><![CDATA[The National Alliance for Medical Image Computing, a roadmap initiative to build a free and open source software infrastructure for translational research in medical image analysis]]></title>
<link>http://jamia.bmj.com/cgi/content/short/19/2/176?rss=1</link>
<description><![CDATA[
<p>The National Alliance for Medical Image Computing (NA-MIC), is a multi-institutional, interdisciplinary community of researchers, who share the recognition that modern health care demands improved technologies to ease suffering and prolong productive life. Organized under the National Centers for Biomedical Computing 7&nbsp;years ago, the mission of NA-MIC is to implement a robust and flexible open-source infrastructure for developing and applying advanced imaging technologies across a range of important biomedical research disciplines. A measure of its success, NA-MIC is now applying this technology to diseases that have immense impact on the duration and quality of life: cancer, heart disease, trauma, and degenerative genetic diseases. The targets of this technology range from group comparisons to subject-specific analysis.</p>
]]></description>
<dc:creator><![CDATA[Kapur, T., Pieper, S., Whitaker, R., Aylward, S., Jakab, M., Schroeder, W., Kikinis, R.]]></dc:creator>
<dc:date>2012-02-07T16:14:26-08:00</dc:date>
<dc:identifier>info:doi/10.1136/amiajnl-2011-000493</dc:identifier>
<dc:identifier>hwp:master-id:amiajnl;amiajnl-2011-000493</dc:identifier>
<dc:publisher>American Medical Informatics Association</dc:publisher>
<dc:title><![CDATA[The National Alliance for Medical Image Computing, a roadmap initiative to build a free and open source software infrastructure for translational research in medical image analysis]]></dc:title>
<prism:publicationDate>2012-03-01</prism:publicationDate>
<prism:section>Brief communication</prism:section>
<prism:volume>19</prism:volume>
<prism:number>2</prism:number>
<prism:startingPage>176</prism:startingPage>
<prism:endingPage>180</prism:endingPage>
</item>
<item rdf:about="http://jamia.bmj.com/cgi/content/short/19/2/181?rss=1">
<title><![CDATA[A translational engine at the national scale: informatics for integrating biology and the bedside]]></title>
<link>http://jamia.bmj.com/cgi/content/short/19/2/181?rss=1</link>
<description><![CDATA[
<p>Informatics for integrating biology and the bedside (i2b2) seeks to provide the instrumentation for using the informational by-products of health care and the biological materials accumulated through the delivery of health care to conduct discovery research and to study the healthcare system in vivo. This complements existing efforts such as prospective cohort studies or trials outside the delivery of routine health care. i2b2 has been used to generate genome-wide studies at less than one tenth the cost and one tenth the time of conventionally performed studies as well as to identify important risk from commonly used medications. i2b2 has been adopted by over 60 academic health centers internationally.</p>
]]></description>
<dc:creator><![CDATA[Kohane, I. S., Churchill, S. E., Murphy, S. N.]]></dc:creator>
<dc:date>2012-02-07T16:14:26-08:00</dc:date>
<dc:identifier>info:doi/10.1136/amiajnl-2011-000492</dc:identifier>
<dc:identifier>hwp:master-id:amiajnl;amiajnl-2011-000492</dc:identifier>
<dc:publisher>American Medical Informatics Association</dc:publisher>
<dc:title><![CDATA[A translational engine at the national scale: informatics for integrating biology and the bedside]]></dc:title>
<prism:publicationDate>2012-03-01</prism:publicationDate>
<prism:section>Brief communication</prism:section>
<prism:volume>19</prism:volume>
<prism:number>2</prism:number>
<prism:startingPage>181</prism:startingPage>
<prism:endingPage>185</prism:endingPage>
</item>
<item rdf:about="http://jamia.bmj.com/cgi/content/short/19/2/186?rss=1">
<title><![CDATA[Simbios: an NIH national center for physics-based simulation of biological structures]]></title>
<link>http://jamia.bmj.com/cgi/content/short/19/2/186?rss=1</link>
<description><![CDATA[
<p>Physics-based simulation provides a powerful framework for understanding biological form and function. Simulations can be used by biologists to study macromolecular assemblies and by clinicians to design treatments for diseases. Simulations help biomedical researchers understand the physical constraints on biological systems as they engineer novel drugs, synthetic tissues, medical devices, and surgical interventions. Although individual biomedical investigators make outstanding contributions to physics-based simulation, the field has been fragmented. Applications are typically limited to a single physical scale, and individual investigators usually must create their own software. These conditions created a major barrier to advancing simulation capabilities. In 2004, we established a National Center for Physics-Based Simulation of Biological Structures (Simbios) to help integrate the field and accelerate biomedical research. In 6&nbsp;years, Simbios has become a vibrant national center, with collaborators in 16 states and eight countries. Simbios focuses on problems at both the molecular scale and the organismal level, with a long-term goal of uniting these in accurate multiscale simulations.</p>
]]></description>
<dc:creator><![CDATA[Delp, S. L., Ku, J. P., Pande, V. S., Sherman, M. A., Altman, R. B.]]></dc:creator>
<dc:date>2012-02-07T16:14:26-08:00</dc:date>
<dc:identifier>info:doi/10.1136/amiajnl-2011-000488</dc:identifier>
<dc:identifier>hwp:master-id:amiajnl;amiajnl-2011-000488</dc:identifier>
<dc:publisher>American Medical Informatics Association</dc:publisher>
<dc:title><![CDATA[Simbios: an NIH national center for physics-based simulation of biological structures]]></dc:title>
<prism:publicationDate>2012-03-01</prism:publicationDate>
<prism:section>Brief communication</prism:section>
<prism:volume>19</prism:volume>
<prism:number>2</prism:number>
<prism:startingPage>186</prism:startingPage>
<prism:endingPage>189</prism:endingPage>
</item>
<item rdf:about="http://jamia.bmj.com/cgi/content/short/19/2/190?rss=1">
<title><![CDATA[The National Center for Biomedical Ontology]]></title>
<link>http://jamia.bmj.com/cgi/content/short/19/2/190?rss=1</link>
<description><![CDATA[
<p>The National Center for Biomedical Ontology is now in its seventh year. The goals of this National Center for Biomedical Computing are to: create and maintain a repository of biomedical ontologies and terminologies; build tools and web services to enable the use of ontologies and terminologies in clinical and translational research; educate their trainees and the scientific community broadly about biomedical ontology and ontology-based technology and best practices; and collaborate with a variety of groups who develop and use ontologies and terminologies in biomedicine. The centerpiece of the National Center for Biomedical Ontology is a web-based resource known as BioPortal. BioPortal makes available for research in computationally useful forms more than 270 of the world's biomedical ontologies and terminologies, and supports a wide range of web services that enable investigators to use the ontologies to annotate and retrieve data, to generate value sets and special-purpose lexicons, and to perform advanced analytics on a wide range of biomedical data.</p>
]]></description>
<dc:creator><![CDATA[Musen, M. A., Noy, N. F., Shah, N. H., Whetzel, P. L., Chute, C. G., Story, M.-A., Smith, B., and the NCBO team]]></dc:creator>
<dc:date>2012-02-07T16:14:26-08:00</dc:date>
<dc:identifier>info:doi/10.1136/amiajnl-2011-000523</dc:identifier>
<dc:identifier>hwp:master-id:amiajnl;amiajnl-2011-000523</dc:identifier>
<dc:publisher>American Medical Informatics Association</dc:publisher>
<dc:title><![CDATA[The National Center for Biomedical Ontology]]></dc:title>
<prism:publicationDate>2012-03-01</prism:publicationDate>
<prism:section>Brief communication</prism:section>
<prism:volume>19</prism:volume>
<prism:number>2</prism:number>
<prism:startingPage>190</prism:startingPage>
<prism:endingPage>195</prism:endingPage>
</item>
<item rdf:about="http://jamia.bmj.com/cgi/content/short/19/2/196?rss=1">
<title><![CDATA[iDASH: integrating data for analysis, anonymization, and sharing]]></title>
<link>http://jamia.bmj.com/cgi/content/short/19/2/196?rss=1</link>
<description><![CDATA[
<p>iDASH (integrating data for analysis, anonymization, and sharing) is the newest National Center for Biomedical Computing funded by the NIH. It focuses on algorithms and tools for sharing data in a privacy-preserving manner. Foundational privacy technology research performed within iDASH is coupled with innovative engineering for collaborative tool development and data-sharing capabilities in a private Health Insurance Portability and Accountability Act (HIPAA)-certified cloud. Driving Biological Projects, which span different biological levels (from molecules to individuals to populations) and focus on various health conditions, help guide research and development within this Center. Furthermore, training and dissemination efforts connect the Center with its stakeholders and educate data owners and data consumers on how to share and use clinical and biological data. Through these various mechanisms, iDASH implements its goal of providing biomedical and behavioral researchers with access to data, software, and a high-performance computing environment, thus enabling them to generate and test new hypotheses.</p>
]]></description>
<dc:creator><![CDATA[Ohno-Machado, L., Bafna, V., Boxwala, A. A., Chapman, B. E., Chapman, W. W., Chaudhuri, K., Day, M. E., Farcas, C., Heintzman, N. D., Jiang, X., Kim, H., Kim, J., Matheny, M. E., Resnic, F. S., Vinterbo, S. A., and the iDASH team]]></dc:creator>
<dc:date>2012-02-07T16:14:26-08:00</dc:date>
<dc:identifier>info:doi/10.1136/amiajnl-2011-000538</dc:identifier>
<dc:identifier>hwp:master-id:amiajnl;amiajnl-2011-000538</dc:identifier>
<dc:publisher>American Medical Informatics Association</dc:publisher>
<dc:title><![CDATA[iDASH: integrating data for analysis, anonymization, and sharing]]></dc:title>
<prism:publicationDate>2012-03-01</prism:publicationDate>
<prism:section>Brief communication</prism:section>
<prism:volume>19</prism:volume>
<prism:number>2</prism:number>
<prism:startingPage>196</prism:startingPage>
<prism:endingPage>201</prism:endingPage>
</item>
<item rdf:about="http://jamia.bmj.com/cgi/content/short/19/2/202?rss=1">
<title><![CDATA[The Center for Computational Biology: resources, achievements, and challenges]]></title>
<link>http://jamia.bmj.com/cgi/content/short/19/2/202?rss=1</link>
<description><![CDATA[
<p>The Center for Computational Biology (CCB) is a multidisciplinary program where biomedical scientists, engineers, and clinicians work jointly to combine modern mathematical and computational techniques, to perform phenotypic and genotypic studies of biological structure, function, and physiology in health and disease. CCB has developed a computational framework built around the Manifold Atlas, an integrated biomedical computing environment that enables statistical inference on biological manifolds. These manifolds model biological structures, features, shapes, and flows, and support sophisticated morphometric and statistical analyses. The Manifold Atlas includes tools, workflows, and services for multimodal population-based modeling and analysis of biological manifolds. The broad spectrum of biomedical topics explored by CCB investigators include the study of normal and pathological brain development, maturation and aging, discovery of associations between neuroimaging and genetic biomarkers, and the modeling, analysis, and visualization of biological shape, form, and size. CCB supports a wide range of short-term and long-term collaborations with outside investigators, which drive the center's computational developments and focus the validation and dissemination of CCB resources to new areas and scientific domains.</p>
]]></description>
<dc:creator><![CDATA[Toga, A. W., Dinov, I. D., Thompson, P. M., Woods, R. P., Van Horn, J. D., Shattuck, D. W., Parker, D. S.]]></dc:creator>
<dc:date>2012-02-07T16:14:26-08:00</dc:date>
<dc:identifier>info:doi/10.1136/amiajnl-2011-000525</dc:identifier>
<dc:identifier>hwp:master-id:amiajnl;amiajnl-2011-000525</dc:identifier>
<dc:publisher>American Medical Informatics Association</dc:publisher>
<dc:title><![CDATA[The Center for Computational Biology: resources, achievements, and challenges]]></dc:title>
<prism:publicationDate>2012-03-01</prism:publicationDate>
<prism:section>Brief communication</prism:section>
<prism:volume>19</prism:volume>
<prism:number>2</prism:number>
<prism:startingPage>202</prism:startingPage>
<prism:endingPage>206</prism:endingPage>
</item>
<item rdf:about="http://jamia.bmj.com/cgi/content/short/19/2/207?rss=1">
<title><![CDATA[Utility of gene-specific algorithms for predicting pathogenicity of uncertain gene variants]]></title>
<link>http://jamia.bmj.com/cgi/content/short/19/2/207?rss=1</link>
<description><![CDATA[
<p>The rapid advance of gene sequencing technologies has produced an unprecedented rate of discovery of genome variation in humans. A growing number of authoritative clinical repositories archive gene variants and disease phenotypes, yet there are currently many more gene variants that lack clear annotation or disease association. To date, there has been very limited coverage of gene-specific predictors in the literature. Here the evaluation is presented of "gene-specific" predictor models based on a na&iuml;ve Bayesian classifier for 20 gene&ndash;disease datasets, containing 3986 variants with clinically characterized patient conditions. The utility of gene-specific prediction is then compared with "all-gene" generalized prediction and also with existing popular predictors. Gene-specific computational prediction models derived from clinically curated gene variant disease datasets often outperform established generalized algorithms for novel and uncertain gene variants.</p>
]]></description>
<dc:creator><![CDATA[Crockett, D. K., Lyon, E., Williams, M. S., Narus, S. P., Facelli, J. C., Mitchell, J. A.]]></dc:creator>
<dc:date>2012-02-07T16:14:26-08:00</dc:date>
<dc:identifier>info:doi/10.1136/amiajnl-2011-000309</dc:identifier>
<dc:identifier>hwp:master-id:amiajnl;amiajnl-2011-000309</dc:identifier>
<dc:publisher>American Medical Informatics Association</dc:publisher>
<dc:title><![CDATA[Utility of gene-specific algorithms for predicting pathogenicity of uncertain gene variants]]></dc:title>
<prism:publicationDate>2012-03-01</prism:publicationDate>
<prism:section>Brief communication</prism:section>
<prism:volume>19</prism:volume>
<prism:number>2</prism:number>
<prism:startingPage>207</prism:startingPage>
<prism:endingPage>211</prism:endingPage>
</item>
<item rdf:about="http://jamia.bmj.com/cgi/content/short/19/1/111?rss=1">
<title><![CDATA[Improving patient safety via automated laboratory-based adverse event grading]]></title>
<link>http://jamia.bmj.com/cgi/content/short/19/1/111?rss=1</link>
<description><![CDATA[
<p>The identification and grading of adverse events (AEs) during the conduct of clinical trials is a labor-intensive and error-prone process. This paper describes and evaluates a software tool developed by City of Hope to automate complex algorithms to assess laboratory results and identify and grade AEs. We compared AEs identified by the automated system with those previously assessed manually, to evaluate missed/misgraded AEs. We also conducted a prospective paired time assessment of automated versus manual AE assessment. We found a substantial improvement in accuracy/completeness with the automated grading tool, which identified an additional 17% of severe grade 3&ndash;4 AEs that had been missed/misgraded manually. The automated system also provided an average time saving of 5.5&nbsp;min per treatment course. With 400 ongoing treatment trials at City of Hope and an average of 1800 laboratory results requiring assessment per study, the implications of these findings for patient safety are enormous.</p>
]]></description>
<dc:creator><![CDATA[Niland, J. C., Stiller, T., Neat, J., Londrc, A., Johnson, D., Pannoni, S.]]></dc:creator>
<dc:date>2011-12-10T07:38:52-08:00</dc:date>
<dc:identifier>info:doi/10.1136/amiajnl-2011-000513</dc:identifier>
<dc:identifier>hwp:master-id:amiajnl;amiajnl-2011-000513</dc:identifier>
<dc:publisher>American Medical Informatics Association</dc:publisher>
<dc:subject><![CDATA[Unlocked]]></dc:subject>
<dc:title><![CDATA[Improving patient safety via automated laboratory-based adverse event grading]]></dc:title>
<prism:publicationDate>2012-01-01</prism:publicationDate>
<prism:section>Brief communication</prism:section>
<prism:volume>19</prism:volume>
<prism:number>1</prism:number>
<prism:startingPage>111</prism:startingPage>
<prism:endingPage>115</prism:endingPage>
</item>
<item rdf:about="http://jamia.bmj.com/cgi/content/short/19/1/134?rss=1">
<title><![CDATA[A global travelers' electronic health record template standard for personal health records]]></title>
<link>http://jamia.bmj.com/cgi/content/short/19/1/134?rss=1</link>
<description><![CDATA[
<p>Tourism as well as international business travel creates health risks for individuals and populations both in host societies and home countries. One strategy to reduce health-related risks to travelers is to provide travelers and relevant caregivers timely, ongoing access to their own health information. Many websites offer health advice for travelers. For example, the WHO and US Department of State offer up-to-date health information about countries relevant to travel. However, little has been done to assure travelers that their medical information is available at the right place and time when the need might arise. Applications of Information and Communication Technology (ICT) utilizing mobile phones for health management are promising tools both for the delivery of healthcare services and the promotion of personal health. This paper describes the project developed by international informaticians under the umbrella of the International Medical Informatics Association. A template capable of becoming an international standard is proposed. This application is available free to anyone who is interested. Furthermore, its source code is made open.</p>
]]></description>
<dc:creator><![CDATA[Li, Y.-C., Detmer, D. E., Shabbir, S.-A., Nguyen, P. A., Jian, W.-S., Mihalas, G. I., Shortliffe, E. H., Tang, P., Haux, R., Kimura, M.]]></dc:creator>
<dc:date>2011-12-10T07:38:52-08:00</dc:date>
<dc:identifier>info:doi/10.1136/amiajnl-2011-000323</dc:identifier>
<dc:identifier>hwp:master-id:amiajnl;amiajnl-2011-000323</dc:identifier>
<dc:publisher>American Medical Informatics Association</dc:publisher>
<dc:subject><![CDATA[Unlocked]]></dc:subject>
<dc:title><![CDATA[A global travelers' electronic health record template standard for personal health records]]></dc:title>
<prism:publicationDate>2012-01-01</prism:publicationDate>
<prism:section>Brief communication</prism:section>
<prism:volume>19</prism:volume>
<prism:number>1</prism:number>
<prism:startingPage>134</prism:startingPage>
<prism:endingPage>136</prism:endingPage>
</item>
<item rdf:about="http://jamia.bmj.com/cgi/content/short/19/1/137?rss=1">
<title><![CDATA[Commercial off-the-shelf consumer health informatics interventions: recommendations for their design, evaluation and redesign]]></title>
<link>http://jamia.bmj.com/cgi/content/short/19/1/137?rss=1</link>
<description><![CDATA[
<sec><st>Objective</st>
<p>The goal of this paper is to describe the successful application of a use case-based evaluation approach to guide the effective design, evaluation and redesign of inexpensive, commercial, off-the-shelf consumer health informatics (CHI) interventions.</p>
</sec>
<sec><st>Design</st>
<p>Researchers developed four CHI intervention use cases representing two distinct patient populations (patients with diabetes with high blood pressure, post-bariatric surgery patients), two commercial off-the-shelf CHI applications (Microsoft HealthVault, Google Health), and related devices (blood pressure monitor, pedometer, weight scale). Three patient proxies tested each intervention for 10&nbsp;days.</p>
</sec>
<sec><st>Measurements</st>
<p>The patient proxies recorded their challenges while completing use case tasks, rating the severity of each challenge based on how much it hindered their use of the intervention. Two independent evaluators categorized the challenges by human factors domain (physical, cognitive, macroergonomic).</p>
</sec>
<sec><st>Results</st>
<p>The use case-based approach resulted in the identification of 122 challenges, with 12% physical, 50% cognitive and 38% macroergonomic. Thirty-nine challenges (32%) were at least moderately severe. Nine of 22 use case tasks (41%) accounted for 72% of the challenges.</p>
</sec>
<sec><st>Limitations</st>
<p>The study used two patient proxies and addressed two specific patient populations and low-cost, off-the-shelf CHI interventions, which may not perfectly generalize to a larger number of proxies, actual patient populations, or other CHI interventions.</p>
</sec>
<sec><st>Conclusion</st>
<p>CHI designers can employ the use case-based evaluation approach to assess the fit of a CHI intervention with patients' health work, in the context of their daily activities and environment, which would be difficult or impossible to evaluate by laboratory-based studies.</p>
</sec>
]]></description>
<dc:creator><![CDATA[Marquard, J. L., Zayas-Caban, T.]]></dc:creator>
<dc:date>2011-12-10T07:38:52-08:00</dc:date>
<dc:identifier>info:doi/10.1136/amiajnl-2011-000338</dc:identifier>
<dc:identifier>hwp:master-id:amiajnl;amiajnl-2011-000338</dc:identifier>
<dc:publisher>American Medical Informatics Association</dc:publisher>
<dc:title><![CDATA[Commercial off-the-shelf consumer health informatics interventions: recommendations for their design, evaluation and redesign]]></dc:title>
<prism:publicationDate>2012-01-01</prism:publicationDate>
<prism:section>Brief communication</prism:section>
<prism:volume>19</prism:volume>
<prism:number>1</prism:number>
<prism:startingPage>137</prism:startingPage>
<prism:endingPage>142</prism:endingPage>
</item>
<item rdf:about="http://jamia.bmj.com/cgi/content/short/18/Suppl_1/i13?rss=1">
<title><![CDATA[Lessons learned from usability testing of the VA's personal health record]]></title>
<link>http://jamia.bmj.com/cgi/content/short/18/Suppl_1/i13?rss=1</link>
<description><![CDATA[
<p>In order to create user-centered design information to guide the development of personal health records (PHRs), 24 patients participated in usability assessments of VA's MyHealth<I>e</I>Vet program. Observational videos and efficiency measures were collected among users performing four PHR scenarios: registration and log-in, prescription refill, tracking health, and searching for health information. Twenty-five percent of users successfully completed registration. Individuals preferred prescription numbers over names, sometimes due to privacy concerns. Only efficiency in prescription refills was significantly better than target values. Users wanted to print their information to share with their doctors, and questioned the value of MyHealth<I>e</I>Vet search functions over existing online health information. In summary, PHR registration must balance simplicity and security, usability tests guide how PHRs can tailor functions to individual preferences, PHRs add value to users' data by making information more accessible and understandable, and healthcare organizations should build trust for PHR health content.</p>
]]></description>
<dc:creator><![CDATA[Haggstrom, D. A., Saleem, J. J., Russ, A. L., Jones, J., Russell, S. A., Chumbler, N. R.]]></dc:creator>
<dc:date>2011-12-16T08:57:23-08:00</dc:date>
<dc:identifier>info:doi/10.1136/amiajnl-2010-000082</dc:identifier>
<dc:identifier>hwp:master-id:amiajnl;amiajnl-2010-000082</dc:identifier>
<dc:publisher>American Medical Informatics Association</dc:publisher>
<dc:title><![CDATA[Lessons learned from usability testing of the VA's personal health record]]></dc:title>
<prism:publicationDate>2011-12-01</prism:publicationDate>
<prism:section>Brief communication</prism:section>
<prism:volume>18</prism:volume>
<prism:number>Suppl 1</prism:number>
<prism:startingPage>i13</prism:startingPage>
<prism:endingPage>i17</prism:endingPage>
</item>
<item rdf:about="http://jamia.bmj.com/cgi/content/short/18/Suppl_1/i18?rss=1">
<title><![CDATA[MyHealthAtVanderbilt: policies and procedures governing patient portal functionality]]></title>
<link>http://jamia.bmj.com/cgi/content/short/18/Suppl_1/i18?rss=1</link>
<description><![CDATA[
<p>Explicit guidelines are needed to develop safe and effective patient portals. This paper proposes general principles, policies, and procedures for patient portal functionality based on MyHealthAtVanderbilt (MHAV), a robust portal for Vanderbilt University Medical Center. We describe policies and procedures designed to govern popular portal functions, address common user concerns, and support adoption. We present the results of our approach as overall and function-specific usage data. Five years after implementation, MHAV has over 129 800 users; 45% have used bi-directional messaging; 52% have viewed test results and 45% have viewed other medical record data; 30% have accessed health education materials; 39% have scheduled appointments; and 29% have managed a medical bill. Our policies and procedures have supported widespread adoption and use of MHAV. We believe other healthcare organizations could employ our general guidelines and lessons learned to facilitate portal implementation and usage.</p>
]]></description>
<dc:creator><![CDATA[Osborn, C. Y., Rosenbloom, S. T., Stenner, S. P., Anders, S., Muse, S., Johnson, K. B., Jirjis, J., Jackson, G. P.]]></dc:creator>
<dc:date>2011-12-16T08:57:23-08:00</dc:date>
<dc:identifier>info:doi/10.1136/amiajnl-2011-000184</dc:identifier>
<dc:identifier>hwp:master-id:amiajnl;amiajnl-2011-000184</dc:identifier>
<dc:publisher>American Medical Informatics Association</dc:publisher>
<dc:title><![CDATA[MyHealthAtVanderbilt: policies and procedures governing patient portal functionality]]></dc:title>
<prism:publicationDate>2011-12-01</prism:publicationDate>
<prism:section>Brief communication</prism:section>
<prism:volume>18</prism:volume>
<prism:number>Suppl 1</prism:number>
<prism:startingPage>i18</prism:startingPage>
<prism:endingPage>i23</prism:endingPage>
</item>
<item rdf:about="http://jamia.bmj.com/cgi/content/short/18/Suppl_1/i24?rss=1">
<title><![CDATA[Patient portal doldrums: does an exam room promotional video during an office visit increase patient portal registrations and portal use?]]></title>
<link>http://jamia.bmj.com/cgi/content/short/18/Suppl_1/i24?rss=1</link>
<description><![CDATA[
<p>The patient portal is a web service which allows patients to view their electronic health record, communicate online with their care teams, and manage healthcare appointments and medications. Despite advantages of the patient portal, registrations for portal use have often been slow. Using a secure video system on our existing exam room electronic health record displays during regular office visits, the authors showed patients a video which promoted use of the patient portal. The authors compared portal registrations and portal use following the video to providing a paper instruction sheet and to a control (no additional portal promotion). From the 12 050 office appointments examined, portal registrations within 45&nbsp;days of the appointment were 11.7%, 7.1%, and 2.5% for video, paper instructions, and control respectively (p&lt;0.0001). Within 6&nbsp;months following the interventions, 3.5% in the video cohort, 1.2% in the paper, and 0.75% of the control patients demonstrated portal use by initiating portal messages to their providers (p&lt;0.0001).</p>
]]></description>
<dc:creator><![CDATA[North, F., Hanna, B. K., Crane, S. J., Smith, S. A., Tulledge-Scheitel, S. M., Stroebel, R. J.]]></dc:creator>
<dc:date>2011-12-16T08:57:23-08:00</dc:date>
<dc:identifier>info:doi/10.1136/amiajnl-2011-000381</dc:identifier>
<dc:identifier>hwp:master-id:amiajnl;amiajnl-2011-000381</dc:identifier>
<dc:publisher>American Medical Informatics Association</dc:publisher>
<dc:title><![CDATA[Patient portal doldrums: does an exam room promotional video during an office visit increase patient portal registrations and portal use?]]></dc:title>
<prism:publicationDate>2011-12-01</prism:publicationDate>
<prism:section>Brief communication</prism:section>
<prism:volume>18</prism:volume>
<prism:number>Suppl 1</prism:number>
<prism:startingPage>i24</prism:startingPage>
<prism:endingPage>i27</prism:endingPage>
</item>
<item rdf:about="http://jamia.bmj.com/cgi/content/short/18/Suppl_1/i87?rss=1">
<title><![CDATA[Clinician characteristics and use of novel electronic health record functionality in primary care]]></title>
<link>http://jamia.bmj.com/cgi/content/short/18/Suppl_1/i87?rss=1</link>
<description><![CDATA[
<sec><st>Background</st>
<p>Conventional wisdom holds that older, busier clinicians who see complex patients are less likely to adopt and use novel electronic health record (EHR) functionality.</p>
</sec>
<sec><st>Methods</st>
<p>To compare the characteristics of clinicians who did and did not use novel EHR functionality, we conducted a retrospective analysis of the intervention arm of a randomized trial of new EHR-based tobacco treatment functionality.</p>
</sec>
<sec><st>Results</st>
<p>The novel functionality was used by 103 of 207 (50%) clinicians. Staff physicians were more likely than trainees to use the functionality (64% vs 37%; p&lt;0.001). Clinicians who graduated more than 10&nbsp;years previously were more likely to use the functionality than those who graduated less than 10&nbsp;years previously (64% vs 42%; p&lt;0.01). Clinicians with higher patient volumes were more likely to use the functionality (lowest quartile of number of patient visits, 25%; 2nd quartile, 38%; 3rd quartile, 65%; highest quartile, 71%; p&lt;0.001). Clinicians who saw patients with more documented problems were more likely to use the functionality (lowest tertile of documented patient problems, 38%; 2nd tertile, 58%; highest tertile, 54%; p=0.04). In multivariable modeling, independent predictors of use were the number of patient visits (OR 1.2 per 100 additional patients; 95% CI 1.1 to 1.4) and number of documented problems (OR 2.9 per average additional problem; 95% CI 1.4 to 6.1).</p>
</sec>
<sec><st>Conclusions</st>
<p>Contrary to conventional wisdom, clinically busier physicians seeing patients with more documented problems were more likely to use novel EHR functionality.</p>
</sec>
]]></description>
<dc:creator><![CDATA[Linder, J. A., Rigotti, N. A., Schneider, L. I., Kelley, J. H. K., Brawarsky, P., Schnipper, J. L., Middleton, B., Haas, J. S.]]></dc:creator>
<dc:date>2011-12-16T08:57:24-08:00</dc:date>
<dc:identifier>info:doi/10.1136/amiajnl-2011-000330</dc:identifier>
<dc:identifier>hwp:master-id:amiajnl;amiajnl-2011-000330</dc:identifier>
<dc:publisher>American Medical Informatics Association</dc:publisher>
<dc:title><![CDATA[Clinician characteristics and use of novel electronic health record functionality in primary care]]></dc:title>
<prism:publicationDate>2011-12-01</prism:publicationDate>
<prism:section>Brief communication</prism:section>
<prism:volume>18</prism:volume>
<prism:number>Suppl 1</prism:number>
<prism:startingPage>i87</prism:startingPage>
<prism:endingPage>i90</prism:endingPage>
</item>
<item rdf:about="http://jamia.bmj.com/cgi/content/short/18/Suppl_1/i91?rss=1">
<title><![CDATA[Tracking the delivery of prevention-oriented care among primary care providers who have adopted electronic health records]]></title>
<link>http://jamia.bmj.com/cgi/content/short/18/Suppl_1/i91?rss=1</link>
<description><![CDATA[
<p>The Primary Care Information Project is a New York City initiative aimed at improving population health through the improved delivery of preventive care. It has assisted with the adoption of a fully functional electronic health record (EHR) in over 300 primary care practices. Practices with EHRs automatically transmit summary data that can be used to track population health indicators for recommended preventive care. Early analysis, focusing on small practices with fewer than 10 providers serving Medicaid and uninsured populations, showed increases in the delivery of recommended services of 0.1&ndash;2.4% per month (p&le;0.05). However, measurement of preventive care across this population is limited by some inconsistency of data transmission. This study shows that EHRs can be used to track the delivery of recommended preventive care across small primary care practices serving lower income communities in which few data are generally available for assessing population health.</p>
]]></description>
<dc:creator><![CDATA[De Leon, S. F., Shih, S. C.]]></dc:creator>
<dc:date>2011-12-16T08:57:24-08:00</dc:date>
<dc:identifier>info:doi/10.1136/amiajnl-2011-000219</dc:identifier>
<dc:identifier>hwp:master-id:amiajnl;amiajnl-2011-000219</dc:identifier>
<dc:publisher>American Medical Informatics Association</dc:publisher>
<dc:title><![CDATA[Tracking the delivery of prevention-oriented care among primary care providers who have adopted electronic health records]]></dc:title>
<prism:publicationDate>2011-12-01</prism:publicationDate>
<prism:section>Brief communication</prism:section>
<prism:volume>18</prism:volume>
<prism:number>Suppl 1</prism:number>
<prism:startingPage>i91</prism:startingPage>
<prism:endingPage>i95</prism:endingPage>
</item>
<item rdf:about="http://jamia.bmj.com/cgi/content/short/18/Suppl_1/i157?rss=1">
<title><![CDATA[Direct2Experts: a pilot national network to demonstrate interoperability among research-networking platforms]]></title>
<link>http://jamia.bmj.com/cgi/content/short/18/Suppl_1/i157?rss=1</link>
<description><![CDATA[
<p>Research-networking tools use data-mining and social networking to enable expertise discovery, matchmaking and collaboration, which are important facets of team science and translational research. Several commercial and academic platforms have been built, and many institutions have deployed these products to help their investigators find local collaborators. Recent studies, though, have shown the growing importance of multiuniversity teams in science. Unfortunately, the lack of a standard data-exchange model and resistance of universities to share information about their faculty have presented barriers to forming an institutionally supported national network. This case report describes an initiative, which, in only 6&nbsp;months, achieved interoperability among seven major research-networking products at 28 universities by taking an approach that focused on addressing institutional concerns and encouraging their participation. With this necessary groundwork in place, the second phase of this effort can begin, which will expand the network's functionality and focus on the end users.</p>
]]></description>
<dc:creator><![CDATA[Weber, G. M., Barnett, W., Conlon, M., Eichmann, D., Kibbe, W., Falk-Krzesinski, H., Halaas, M., Johnson, L., Meeks, E., Mitchell, D., Schleyer, T., Stallings, S., Warden, M., Kahlon, M., Members of the Direct2Experts Collaboration]]></dc:creator>
<dc:date>2011-12-16T08:57:24-08:00</dc:date>
<dc:identifier>info:doi/10.1136/amiajnl-2011-000200</dc:identifier>
<dc:identifier>hwp:master-id:amiajnl;amiajnl-2011-000200</dc:identifier>
<dc:publisher>American Medical Informatics Association</dc:publisher>
<dc:title><![CDATA[Direct2Experts: a pilot national network to demonstrate interoperability among research-networking platforms]]></dc:title>
<prism:publicationDate>2011-12-01</prism:publicationDate>
<prism:section>Brief communication</prism:section>
<prism:volume>18</prism:volume>
<prism:number>Suppl 1</prism:number>
<prism:startingPage>i157</prism:startingPage>
<prism:endingPage>i160</prism:endingPage>
</item>
<item rdf:about="http://jamia.bmj.com/cgi/content/short/18/Suppl_1/i161?rss=1">
<title><![CDATA[The NIAID Division of AIDS enterprise information system: integrated decision support for global clinical research programs]]></title>
<link>http://jamia.bmj.com/cgi/content/short/18/Suppl_1/i161?rss=1</link>
<description><![CDATA[
<p>The National Institute of Allergy and Infectious Diseases (NIAID) Division of AIDS (DAIDS) Enterprise Information System (DAIDS-ES) is a web-based system that supports NIAID in the scientific, strategic, and tactical management of its global clinical research programs for HIV/AIDS vaccines, prevention, and therapeutics. Different from most commercial clinical trials information systems, which are typically protocol-driven, the DAIDS-ES was built to exchange information with those types of systems and integrate it in ways that help scientific program directors lead the research effort and keep pace with the complex and ever-changing global HIV/AIDS pandemic. Whereas commercially available clinical trials support systems are not usually disease-focused, DAIDS-ES was specifically designed to capture and incorporate unique scientific, demographic, and logistical aspects of HIV/AIDS treatment, prevention, and vaccine research in order to provide a rich source of information to guide informed decision-making. Sharing data across its internal components and with external systems, using defined vocabularies, open standards and flexible interfaces, the DAIDS-ES enables NIAID, its global collaborators and stakeholders, access to timely, quality information about NIAID-supported clinical trials which is utilized to: (1) analyze the research portfolio, assess capacity, identify opportunities, and avoid redundancies; (2) help support study safety, quality, ethics, and regulatory compliance; (3) conduct evidence-based policy analysis and business process re-engineering for improved efficiency. This report summarizes how the DAIDS-ES was conceptualized, how it differs from typical clinical trial support systems, the rationale for key design choices, and examples of how it is being used to advance the efficiency and effectiveness of NIAID's HIV/AIDS clinical research programs.</p>
]]></description>
<dc:creator><![CDATA[Kagan, J. M., Gupta, N., Varghese, S., Virkar, H.]]></dc:creator>
<dc:date>2011-12-16T08:57:24-08:00</dc:date>
<dc:identifier>info:doi/10.1136/amiajnl-2011-000114</dc:identifier>
<dc:identifier>hwp:master-id:amiajnl;amiajnl-2011-000114</dc:identifier>
<dc:publisher>American Medical Informatics Association</dc:publisher>
<dc:title><![CDATA[The NIAID Division of AIDS enterprise information system: integrated decision support for global clinical research programs]]></dc:title>
<prism:publicationDate>2011-12-01</prism:publicationDate>
<prism:section>Brief communication</prism:section>
<prism:volume>18</prism:volume>
<prism:number>Suppl 1</prism:number>
<prism:startingPage>i161</prism:startingPage>
<prism:endingPage>i165</prism:endingPage>
</item>
<item rdf:about="http://jamia.bmj.com/cgi/content/short/18/6/875?rss=1">
<title><![CDATA[Understanding the mobile internet to develop the next generation of online medical teaching tools]]></title>
<link>http://jamia.bmj.com/cgi/content/short/18/6/875?rss=1</link>
<description><![CDATA[
<p>Healthcare providers (HCPs) use online medical information for self-directed learning and patient care. Recently, the mobile internet has emerged as a new platform for accessing medical information as it allows mobile devices to access online information in a manner compatible with their restricted storage. We investigated mobile internet usage parameters to direct the future development of mobile internet teaching websites. Nephrology On-Demand Mobile (NOD<sup>M</sup>) (<A HREF="http://www.nephrologyondemand.org">http://www.nephrologyondemand.org</A>) was made accessible to all mobile devices. From February 1 to December 31, 2010, HCP use of NOD<sup>M</sup> was tracked using code inserted into the root files. Nephrology On-Demand received 15 258 visits, of which approximately 10% were made to NOD<sup>M</sup>, with the majority coming from the USA. Most access to NOD<sup>M</sup> was through the Apple iOS family of devices and cellular connections were the most frequently used. These findings provide a basis for the future development of mobile nephrology and medical teaching tools.</p>
]]></description>
<dc:creator><![CDATA[Desai, T., Christiano, C., Ferris, M.]]></dc:creator>
<dc:date>2011-10-18T14:19:35-07:00</dc:date>
<dc:identifier>info:doi/10.1136/amiajnl-2011-000259</dc:identifier>
<dc:identifier>hwp:master-id:amiajnl;amiajnl-2011-000259</dc:identifier>
<dc:publisher>American Medical Informatics Association</dc:publisher>
<dc:title><![CDATA[Understanding the mobile internet to develop the next generation of online medical teaching tools]]></dc:title>
<prism:publicationDate>2011-11-01</prism:publicationDate>
<prism:section>Brief communication</prism:section>
<prism:volume>18</prism:volume>
<prism:number>6</prism:number>
<prism:startingPage>875</prism:startingPage>
<prism:endingPage>878</prism:endingPage>
</item>
<item rdf:about="http://jamia.bmj.com/cgi/content/short/18/5/717?rss=1">
<title><![CDATA[Improving the validity of determining medication adherence from electronic health record medications orders]]></title>
<link>http://jamia.bmj.com/cgi/content/short/18/5/717?rss=1</link>
<description><![CDATA[
<p>We developed an accurate and valid medication order algorithm to identify from electronic health records the definitive medication order intended for dispensing and applied this process to identify a cohort of patients and to stratify them into one of three medication adherence groups: early non-persistence, primary non-adherence, or ongoing adherence. We identified medication order data from electronic health record tables, obtained the orders, and linked the orders to dispensings. These steps were then used to identify patients newly prescribed antihypertensive, antidiabetic, or antihyperlipidemic medications and to determine the adherence group of each patient. Record review validated each process step, thus increasing the accuracy of group assignment as well as the criteria used to select patients. This work is an important first step to accurately identify study-specific patient adherence cohorts and allow more comprehensive estimates of population medication adherence.</p>
]]></description>
<dc:creator><![CDATA[Carroll, N. M., Ellis, J. L., Luckett, C. F., Raebel, M. A.]]></dc:creator>
<dc:date>2011-08-16T13:07:37-07:00</dc:date>
<dc:identifier>info:doi/10.1136/amiajnl-2011-000151</dc:identifier>
<dc:identifier>hwp:master-id:amiajnl;amiajnl-2011-000151</dc:identifier>
<dc:publisher>American Medical Informatics Association</dc:publisher>
<dc:title><![CDATA[Improving the validity of determining medication adherence from electronic health record medications orders]]></dc:title>
<prism:publicationDate>2011-09-01</prism:publicationDate>
<prism:section>Brief communication</prism:section>
<prism:volume>18</prism:volume>
<prism:number>5</prism:number>
<prism:startingPage>717</prism:startingPage>
<prism:endingPage>720</prism:endingPage>
</item>
</rdf:RDF>
